Events in 2023
Webinar: Design and Analysis of N-of-1 trials
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Dates: 31st January and 7th February 2023
Location: Virtual webinars (x 2)
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Facilitators: Dr Suzanne McDonald and Professor James McGree
Description: This was a 2 part webinar covering the design and analysis of N-of-1 trials. In webinar 1, Dr Suzanne McDonald described the basic principles of N-of-1 trial designs using illustrative examples, provided an overview of other types of single-case designs, and discussed key developments that have occurred in the field over the past decade. In webinar 2, Dr Suzanne McDonald and Professor James McGree described common techniques used to evaluate data from individual and aggregated N-of-1 trials and discussed central topics including autocorrelation and sample size determination.
This event was hosted by the INFORM RARE and the University of Ottawa. To find out more, contact Dr Suzanne McDonald.
Webinar: ACTA STInG: N-of-1 Trials Webinar Series
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Dates: 18th April (webinar 1) & 2nd May (webinar 2) 2023
Location: Virtual webinars
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Facilitator: Professor Stephen Senn
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Description: This was a 2-part webinar series covering the design and analysis of N-of-1 trials. N-of-1 trials are experiments in which patients are systematically allocated to repeated episodes of treatment with interventions, typically pharmaceuticals, whose effects are being compared. Traditionally, N-of-1 trials have been analysed independently on a patient-by-patient basis but this four-lecture course will consider the design and analysis of sets of N-of-1 trials, that is to say involving many patients, with various objectives, for example, not only to study the average effects of treatments but also to identify differences in individual response. The emphasis of the course was practical and philosophical and mathematical development was kept to a minimum. Analysis in R, SAS and Genstat was covered. ​Webinar 1 introduced the topic and considered some relevant history. This session concentrated on using N-of-1 trials to estimate average treatment effects and considered both randomisation approaches and fixed linear models. Webinar 2 was concerned with estimating individual effects using mixed models with random subject effects, and also considered the planning of N-of-1 trials
This event was hosted by the Australian Clinical Trials Alliance. To find out more, visit the webpages for webinar 1 and webinar 2.
Symposium: Small is Beautiful {Once More}
Date: 24th-27th April 2023
Location: Virtual Symposium
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Coordinators: Johan W.S. Vlaeyen, Patrick Onghena, Livia Guadagnoli, Rikard Wicksell, and Eva Ceulemans
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Description: Within-person research has exponentially increased in recent years. Clinicians and researchers alike are benefiting from the flexibility and potential of research methods focusing on the individual. The result of such staggering interest has culminated in the current symposium, which strives to bring together experts and novices in this growing field of research. We aim to continue expanding awareness, knowledge, and expertise of this increasingly prominent research methodology. The general theme of the symposium will be bringing together the two worlds of single case designs: Single Case Observational Designs (SCODs) and Single-Case Experimental Designs (SCEDs).
Host: This event was hosted by KU Leuven and Karolinska Institutet. To find out more, visit the event website.
