Blog

SHORT BLOGS AND SELECTED PAPERS

Below you will find a list of short blogs and selected papers. New blogs and papers are added on a monthly basis.To receive updates about new posts by email, please join the ICN.

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Apr 30
3 min

Progress Towards Priorities for the International Collaborative Network for N-of-1 Trials and SCDs

Describes progress towards priorities for the ICN

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Jan 30
1 min

Protocol for a Randomized Controlled Trial Enhanced with Single-Case Experimental Design

Selected article written by Simons, Harrison, O'Brien, Heirich, Loecher, Boothroyd, Vlaeyen, Wicksell, Schofield, Hood, Orendurff, Chan & Lyons (2019) Summar...

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Jan 30
3 min

Visualization of Individual Data: A Powerful Tool in Personalized Medicine

Authors: Kenneth Shulman, Amparo Casanova & Marina Vives-Metres

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Sep 30, 2019
3 min

Going Paperless: How Digital Technology Can Shape the Field of N-of-1 Trials

Authors: Samuel Tan, Farhad Fatehi, Steve Donoghue and Sandy Bodner

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Sep 30, 2019
1 min

Patient, study thyself

Selected article written by Wicks (2019)

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Aug 30, 2019
1 min

A Pilot Study of Amino Acids in Unresectable Non-Small-Cell Lung Cancer Patients During Chemotherapy

Selected paper written by Lian Liu, Yue Zhang, Jia Wei, Zhaoxin Chen, and Jing Yu (2019)

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Aug 30, 2019
3 min

N-of-1 Trials in CAM: The New Frontier for Generating Practice-Based Evidence?

Authors: Dr Joanne Bradbury, Prof Sandra Grace and Dr Cathy Avila A system of healthcare that does not recognise traditional complementary and alternative me...

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May 31, 2019
2 min

The Rare Disease Registry and Analytics Platform: Paving the way forward for N-of-1 trials

Authors: Dr James McGree and Samuel Tan Progress towards a global rare disease registry An MTPConnect funded project is currently underway at the Queensland ...

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May 31, 2019
1 min

Designing Robust N-of-1 Studies for Precision Medicine

Read this month's ICN selected paper!

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Apr 30, 2019
1 min

Personalised Nutrition and Health

Authors: Dr Jose M Ordovas, Dr Lynnette R Ferguson, Dr E Shyong Tai, Dr John C Mathers Summary: In this informative review, Ordovas and colleagues discuss th...

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Apr 30, 2019
4 min

Is There a Role for N-of-1 Trials in Nutrition Research?

Author: Dr Veronique Chachay As a key component of evidence-based healthcare, nutrition research provides insight into a number of significant issues: the me...

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Mar 31, 2019
1 min

Meta-Analysis of Single-Case Research via Multilevel Models

Authors: Dr Mariola Moeyaert, Dr Rumen Manolov, and Dr Emily Rodabaugh Multilevel modeling is an approach that can be used to summarize single case experimen...

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Mar 31, 2019
3 min

Evaluation of a Physical Activity Intervention for Individuals with Whiplash Associated Disorders

Authors: Dr Carrie Ritchie, Dr Kelly Clanchy, Dr Sean Tweedy, Dr Melissa Day, A/Prof. Jane Nikles, Prof. Robyn Tate, Prof. Michele Sterling A research projec...

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Feb 28, 2019
4 min

Using N-of-1 Trials to Identify Responders to Melatonin for Sleep Disturbance in Parkinson's Disease

Study in progress! Authors: Dr Jane Nikles, A/Prof. John O’Sullivan, Prof. Geoff Mitchell, Dr Alex Ritchie, A/Prof. Simon Smith, Dr Hugh Senior, A/Prof James...

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Feb 28, 2019
1 min

A SCED Study on Improving Social Communication Skills after Traumatic Brain Injury

Authors: Dr Rachael Rietdijk, Emma Power, Melissa Brunner, Dr Leanne Togher Summary This paper describes a SCED to evaluate telehealth to deliver social comm...

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Jan 31, 2019
3 min

Effect of mexiletine on muscle stiffness in nondystrophic myotonia: aggregated N-of-1 trials

Full title: Effect of mexiletine on muscle stiffness in patients with nondystrophic myotonia evaluated using aggregated N-of-1 trials: a clinical and validat...

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Jan 31, 2019
1 min

Evaluation of person-level heterogeneity of treatment effects in multiperson N-of-1 studies

Full title: Evaluation of person-level heterogeneity of treatment effects in published multiperson N-of-1 studies: systematic review and reanalysis Authors: ...

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Dec 31, 2018
3 min

10 key take-home messages from an expert workshop on single-case methodology

Author: Dr Suzanne McDonald Single-case (or ‘n-of-1’) methodology provides researchers and clinicians with a flexible and rigorous alternative to using group...

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Dec 31, 2018
1 min

Statistical pitfalls of personalized medicine

Author: Stephen Senn This article describes some key assumptions that have been made in personalised medicine. For example: There is a tendency to believe th...

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Nov 30, 2018
3 min

Personalised treatments for acute whiplash injuries: A pilot study

Authors: Dr Jane Nikles and Sherin Jacob Study summary WORK IN PROGRESS! We are applying Bayesian modelling of prior data for a population with acute injury,...

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