Single-Case Studies as a Hot Topic in Pain Research: A Conference Review
Author: Sara Laureen Bartels The 12th Congress of the European Pain Federation EFIC 2022 took place in Dublin in a hybrid format from...
The International Collaborative Network for N-of-1 Trials and Single-Case Designs
BLOGS AND SELECTED PAPERS
New blogs and selected papers are added on a monthly basis. To receive updates about new posts by email, please join the ICN.
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- May 13
- 5 min
An Interview with Professor Nicholas Schork, Thought Leader in the Field of Single-Case Designs
Dr. Nicholas Schork is Deputy Director and Distinguished Professor of Quantitative Medicine at The Translational Genomics Research...
205 views0 comments
- Aug 22, 2021
- 6 min
Brave New World of Health Care Consumerism, N-of-1, and Character of Health Type
Author: Browning Rockwell, WeWa.life The ICN is a noncommercial entity that receives no funding and is run by volunteers. The ICN...
120 views0 comments
- Jul 1, 2021
- 5 min
Implementing Single-Case Designs in Complementary and Alternative Medicine Trials
Authors: Joanne Bradbury and Sandra Grace In many ways, N-of-1 trials are well-suited to complementary and alternative medicine (CAM)...
118 views0 comments
- May 31, 2021
- 4 min
Who Will Benefit from Which Diet: Can N-of-1 Studies Fill a Gap in the Care of Adult PKU?
Authors: Maria Depenweiller, Kathryn Moseley, Kirsten Ahring, Ash Morgan Chambers & Annie Prince In phenylketonuria (PKU), a rare...
130 views0 comments
- Mar 30, 2021
- 5 min
Will the Real Mr. Average Please Stand Up?
Authors: Anne MacGregor & Alec Mian We can easily recognize the face of someone we know from thousands if not millions of other humans....
184 views1 comment
- Nov 30, 2020
- 4 min
N-of-1 Trials are Valuable Scientific Methods for Precision Medicine
Authors: Suzanne McDonald, James McGree & Jane Nikles We were interested to see the reference to N-of-1 trials in the article by...
449 views0 comments
- Oct 31, 2020
- 4 min
Creating Evidence from Real World Patient Digital Data
Authors: Jane Nikles, Eric J. Daza, Suzanne McDonald, Eric Hekler and Nicholas Schork The number of published N-of-1 articles has doubled...
335 views0 comments
- Jun 30, 2020
- 5 min
N-of-1 Trials in Practice: A Training Program for Complementary Medicine Practitioners
Dr Joanne Bradbury and Professor Sandra Grace discuss a training program for complementary medicine practitioners
56 views0 comments
- May 31, 2020
- 3 min
Progress Towards Priorities for the International Collaborative Network for N-of-1 Trials and SCDs
Describes progress towards priorities for the ICN
79 views0 comments
- Jan 30, 2020
- 3 min
Visualization of Individual Data: A Powerful Tool in Personalized Medicine
Authors: Kenneth Shulman, Amparo Casanova & Marina Vives-Metres
131 views0 comments
- Sep 30, 2019
- 3 min
Going Paperless: How Digital Technology Can Shape the Field of N-of-1 Trials
Authors: Samuel Tan, Farhad Fatehi, Steve Donoghue and Sandy Bodner
172 views0 comments
- Aug 30, 2019
- 3 min
N-of-1 Trials in CAM: The New Frontier for Generating Practice-Based Evidence?
Authors: Dr Joanne Bradbury, Prof Sandra Grace and Dr Cathy Avila A system of healthcare that does not recognise traditional...
112 views0 comments
- May 31, 2019
- 2 min
The Rare Disease Registry and Analytics Platform: Paving the way forward for N-of-1 trials
Authors: Dr James McGree and Samuel Tan Progress towards a global rare disease registry An MTPConnect funded project is currently...
113 views0 comments
- Apr 30, 2019
- 4 min
Is There a Role for N-of-1 Trials in Nutrition Research?
Author: Dr Veronique Chachay As a key component of evidence-based healthcare, nutrition research provides insight into a number of...
73 views0 comments
- Mar 31, 2019
- 3 min
Evaluation of a Physical Activity Intervention for Individuals with Whiplash Associated Disorders
Authors: Dr Carrie Ritchie, Dr Kelly Clanchy, Dr Sean Tweedy, Dr Melissa Day, A/Prof. Jane Nikles, Prof. Robyn Tate, Prof. Michele...
61 views0 comments
- Feb 28, 2019
- 4 min
Using N-of-1 Trials to Identify Responders to Melatonin for Sleep Disturbance in Parkinson's Disease
Study in progress! Authors: Dr Jane Nikles, A/Prof. John O’Sullivan, Prof. Geoff Mitchell, Dr Alex Ritchie, A/Prof. Simon Smith, Dr Hugh...
88 views0 comments
- Jan 31, 2019
- 3 min
Effect of mexiletine on muscle stiffness in nondystrophic myotonia: aggregated N-of-1 trials
Full title: Effect of mexiletine on muscle stiffness in patients with nondystrophic myotonia evaluated using aggregated N-of-1 trials: a...
61 views0 comments
- Dec 31, 2018
- 3 min
10 key take-home messages from an expert workshop on single-case methodology
Author: Dr Suzanne McDonald Single-case (or ‘n-of-1’) methodology provides researchers and clinicians with a flexible and rigorous...
95 views0 comments
- Nov 30, 2018
- 3 min
Personalised treatments for acute whiplash injuries: A pilot study
Authors: Dr Jane Nikles and Sherin Jacob Study summary WORK IN PROGRESS! We are applying Bayesian modelling of prior data for a...
30 views1 comment